Archivo: The Scientist

The Pangenome: Are Single Reference Genomes Dead?
Researchers are abandoning the concept of a list of genes sequenced from a single individual, instead aiming for a way to describe all the genetic variation within a species.

Artificial Ion Pump Mimics Neuronal Speed, Precision
Researchers create an artificial nerve that could be the forerunner of neural prosthetics.

The Genes Underlying Autism Are Coming Into Focus
As researchers sequence the DNA of thousands of kids with autism, dozens of genetic subgroups are emerging.

How Fats Influence the Microbiome
Mice fed a diet high in saturated fat show shifts in their gut microbes and develop obesity-related inflammation.

Genomic Elements Reveal Human Diversity
Duplication of copy number variants may be the source of greatest diversity among people, researchers find.

Circadian Clock Transplant
Scientists establish a functional circadian rhythm in bacteria that don’t possess one naturally.

Seasonal Genes
Gene expression varies not only during the day but also throughout the year, a study shows.

Combatting Viruses with RNA-Targeted CRISPR
Scientists reengineer a Cas9 enzyme that naturally targets bacterial RNA to stymie hepatitis C inside human cells.

Growing Human Guts in Mice
Researchers make more progress toward growing human intestines in mice, paving the way for better models of intestinal function and failure.

Stress Fractures
Social adversity shapes humans’ immune systems—and probably their susceptibility to disease—by altering the expression of large groups of genes.